Search on: COMPLEMENT C4A 
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Descriptor English:   Complement C4a 
Descriptor Spanish:   Complemento C4a 
Descriptor Portuguese:   Complemento C4a 
Tree Number:   D12.776.124.486.274.024.260
D12.776.124.486.274.350.250
Definition English:   The smaller fragment formed when complement C4 is cleaved by COMPLEMENT C1S. It is an anaphylatoxin that causes symptoms of immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE) but its activity is weaker than that of COMPLEMENT C3A or COMPLEMENT C5A. 
Pharmacological Action:   Immunologic Factors
 
History Note English:   2006 (1990) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   24578 
Unique Identifier:   D015934 

Occurrence in VHL: 		 

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